Kawasaki disease in a northern region of Italy

Results Male-to-female ratio was 1 to 1. Median age at onset: 35,8 months (2-101 months); children < 6 months: 23%. Complete KD: 73%. Age was not significant different between complete and incomplete KD. Season of Onset of disease : winter in 35%, spring 31%, summer 11%, autumn 23%. Diagnostic signs: iperemic conjunctivitis and mucositis in 92% of pts, cutaneous rash in 88%, linfoadenopathy in 54%, alterations of extremities in 50%, desquamation of extremities in 58%; adjunctive signs: perineal dermatitis in 30% and diarrhea in 42%. 7 pts (5 boys) developed coronary involvement (group1): markers of inflammation and age at onset were not significantly different between group 1 and group 2 (without cardiac abnormalities). 28% of pts in group 1 was responder to therapy versus 47% in group 2. Coronary involvement regressed in all but 2 pts (both received late treatment).